There is no single daily ashwagandha dose that suits everyone. In clinical trials, the most studied doses sit between 300 and 600 mg of extract per day, taken in one or two servings 1. But there is an important nuance: the dose in milligrams only makes sense when you know which extract it is and its concentration of withanolides — the compounds that research links to the studied effects. Two products with "300 mg" on the label may not be comparable.
This page explains what the science shows about doses, how to interpret a supplement label, what the TuttiBear gummies say and when the decision should go through a healthcare professional.
What ashwagandha doses have been studied in clinical trials?
The most cited reference for ashwagandha dose comes from a meta-analysis of 12 randomised trials with 1002 participants (adults aged 25 to 48), which found significant reductions in anxiety and stress levels compared with placebo. In that analysis, the non-linear dose-response model suggested a favourable effect on stress in the range of 300 to 600 mg per day 1. It is important to note that the certainty of the evidence was rated as low by the authors themselves — that is, the results are promising but not definitive.
A more recent meta-analysis, with 22 randomised trials, again found significant improvements in stress, anxiety and depression with ashwagandha supplementation, and identified a linear and non-linear association between the dose given and the effects 2. This reinforces the idea that there is a dose range with more support, but it does not allow us to say that "more is better".
There are also trials with considerably lower doses. In a randomised, double-blind, placebo-controlled study, 60 adults with high self-reported stress took 240 mg of a standardised ashwagandha extract per day for 60 days, with significant reductions in morning cortisol and improvements on anxiety scales compared with placebo 3. And an 8-week trial in healthy adults used only 30 mg per day of an optimised extract, with improvements in cardiorespiratory capacity and perceived fatigue 4. These examples show that the effective dose depends heavily on the type of extract and its standardisation, not just the number of milligrams.
If you are starting out, the most sensible approach is to choose a lower dose within the studied range — for example, 300 mg per day — and observe how you feel. After a week or two, if you notice no effect, you can increase gradually, up to a maximum of 600 mg per day, unless your doctor advises otherwise. Some people do well on lower doses, others need more. There is no universal rule.
Why milligrams alone are not enough to compare products
Ashwagandha extracts are often standardised for withanolides, but the percentage varies widely between products. A 300 mg extract with 5% withanolides provides 15 mg of these compounds; another with 10% provides 30 mg. The total weight is the same, but the amount of active compounds is double. So comparing only milligrams between brands can be misleading.
In addition, the part of the plant used (root, root and leaf) and the extraction method influence the final profile. Clinical trials describe specific extracts, often with a defined standardisation — and it is that description that allows the dose to be interpreted. If a label does not state the withanolide concentration or the plant part, the information is insufficient to know what you are taking.
A more concentrated extract is not necessarily better. Very high doses of withanolides may be more than you need and increase the risk of side effects.
What the Stress Relief Gummies label says
TuttiBear Stress Relief Gummies provide 300 mg of ashwagandha extract per 2-gummy serving, plus 100 mg of L-theanine, 100 mg of GABA, 25 µg of vitamin D3 and 500 µg of vitamin B12. The directions say to chew 2 gummies per day, preferably after a meal. The jar contains 60 gummies, that is, 30 servings.
Compared with the evidence: the 300 mg per serving sits at the lower end of the 300 to 600 mg per day range that the 2022 meta-analysis associated with effects on stress 1. This does not mean the gummy produces the same results as the trials — the formulations, populations and designs are different. It only means that the dose per serving is within the range that research has examined. And, as always, doses used in studies are not dosing instructions: follow the directions on the label.
The vitamin D3 and vitamin B12 in the formula have authorised health claims in the EU — for example, vitamin D contributes to the normal function of the immune system and vitamin B12 contributes to the normal functioning of the nervous system 5. These claims apply to the vitamins, not to the ashwagandha extract, for which there are no authorised health claims in the EU 5.
How to read the label: dose per gummy versus dose per serving
A common mistake is confusing the amount per gummy with the amount per serving. Many supplements state the value per gummy, but the recommended serving may be two or three. If you take only one gummy, you get half or a third of the dose intended by the manufacturer.
Checklist for reading an ashwagandha supplement label:
- Dose per serving: how many gummies or capsules make up the recommended daily serving?
- Amount of extract: how many milligrams of extract per serving?
- Standardisation: does the label state the percentage of withanolides? If so, calculate the actual amount (for example, 5% of 300 mg = 15 mg).
- Plant part: root, root and leaf, or full-spectrum extract?
- Directions: with or without food? One or two servings?
- Warnings: contraindications and populations for which it is not recommended.
If the label does not state the withanolide percentage, do not invent an interpretation. You can contact the manufacturer or choose a more transparent product. Lack of information is, in itself, a signal to consider.
In food supplements, it is common to see values such as "%NRV" (Nutrient Reference Value). These values refer to vitamins and minerals, based on a standard 2000 kcal diet. For plant extracts like ashwagandha, there is no defined NRV. So do not be surprised if you do not see that percentage — it simply does not apply. What matters is the dose of extract and the concentration of active compounds, not a reference percentage.
Is there a maximum dose? What happens if you take too much?
Research has not established a universal safe maximum dose for ashwagandha. In the trials included in the meta-analyses, the most frequent doses go up to 600 mg per day, with some studies using higher values 1. In a systematic review of 9 studies in people with stress, durations ranged from 30 to 112 days and supplementation reduced cortisol secretion without significant adverse effects — but the authors noted that no study assessed the impact of that reduction on adrenal function in the long term 6.
The most reported side effects in clinical trials are gastrointestinal and generally mild. In a meta-analysis on sleep with 5 trials and 400 participants, no serious side effects were reported 7. Even so, taking much more than the studied dose brings no predictable additional benefit and increases the likelihood of discomfort. If you feel nausea, diarrhoea or unusual drowsiness, stop and speak with a healthcare professional.
If you take a very high dose, the most common symptoms are nausea, diarrhoea and drowsiness. If that happens, stop and speak with a healthcare professional. In case of severe overdose, seek medical help immediately.
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How long until you feel an effect?
Ashwagandha is not fast-acting. Trial durations typically range from 4 to 12 weeks. In the meta-analysis on sleep, the effects were more evident in adults with diagnosed insomnia, with doses ≥600 mg per day and durations ≥8 weeks 7. In the systematic review on cortisol, the studies lasted between 30 and 112 days 6.
This suggests that, if you decide to try it, it makes sense to keep using it consistently for at least 4 to 8 weeks before drawing conclusions. If after that period you notice no difference, it is possible that ashwagandha is not the answer for you — individual response varies and there are no guarantees.
If after 8 weeks you feel no difference, it may be that this plant is not for you. There is no shame in that — individual response varies widely. You can also talk to a pharmacist or doctor to adjust the dose or consider other approaches.
Ashwagandha in gummies: what changes about the dose?
Gummies are a convenient format, but they have practical implications. A single gummy usually contains less extract than a capsule, because the size is limited — so you may need to take two or more to reach the dose per serving. Always check how many gummies equal the daily dose.
There are no studies directly comparing the absorption of ashwagandha in gummies with that in capsules. Clinical trials mostly use capsule extracts, and there are no data that allow us to claim equivalence or superiority between forms. What is known is that absorption can vary with the formulation, so the practical reference is the manufacturer's directions. To go deeper into this comparison, see the article Ashwagandha gummies or tablets: which should you choose?.
Gummies may also contain sweeteners or other ingredients. Stress Relief Gummies, for example, contain polyols (maltitol) and the warning states that excessive consumption may have a laxative effect. If you are monitoring your intake of sugars or polyols, it is worth reading the full ingredient list.
If you are watching your sugar intake, check the label: gummies may contain sugar or other ingredients. Sugar does not invalidate the supplement, but it is a factor to consider.
When should you talk to a professional before taking it?
There are situations where the decision should not be made alone. If you are pregnant or breastfeeding, if you have children at home, if you take medicines (especially for thyroid, diabetes or blood pressure) or if you have an autoimmune or liver condition, talk to a doctor or pharmacist before starting. The evidence in some of these populations is limited or non-existent, and the precautionary principle applies.
The warnings on Stress Relief Gummies themselves state that the product is not recommended for children, pregnant or breastfeeding women, or people with thyroid disease or autoimmune diseases, and that in case of liver disease, other diseases or taking medicines you should consult a healthcare professional. They may cause drowsiness; if this occurs, do not drive or use machines.
For a broader view of safety and contraindications, see Does ashwagandha have side effects? What to know before taking it. And if your question is about the best time of day, see Ashwagandha: when to take it, morning or night?.
If you do not have easy access to a healthcare professional, at least read the label warnings and respect the contraindications. This is not a question to ask an online forum.
Practical summary
| Question | What the evidence indicates |
|---|---|
| Most studied dose | 300–600 mg per day in the 2022 meta-analysis on stress and anxiety 1 |
| Lower doses with effect | 240 mg/day for 60 days in a trial in adults with high self-reported stress 3; 30 mg/day for 8 weeks in a trial in healthy adults 4 |
| Typical trial duration | 4 to 12 weeks; effects on sleep more evident from 8 weeks 7 |
| Maximum safe dose | Not universally established; a review of 9 studies did not assess long-term effects on adrenal function 6 |
| TuttiBear gummies | 300 mg of ashwagandha extract per 2-gummy serving; directions: 2 gummies per day after a meal |
In short: the 300 to 600 mg per day range is the most studied, but the right dose depends on the extract, the standardisation and your individual response. Start with the dose stated on the label, keep using it consistently for a few weeks and, if you have doubts or relevant health conditions, talk to a professional. To learn more about the plant and its compounds, see the ingredient page Ashwagandha and the article Ashwagandha: benefits, what science says and how to take it.
Frequently asked questions
What is the recommended daily dose of ashwagandha?
There is no single official dose. In clinical trials, the most studied doses sit between 300 and 600 mg of extract per day, but the effective dose depends on the type of extract and its withanolide concentration. Always follow the dose stated on the label of the product you choose.
Can I take ashwagandha at night?
Yes, many people take ashwagandha at night, especially if they are looking for support with sleep. The trials that assessed sleep used durations of at least 8 weeks in some cases. If you feel drowsy during the day, you can adjust the timing or talk to a healthcare professional.
How long does ashwagandha take to work?
Clinical trials usually last between 4 and 12 weeks, and effects on sleep were more evident from 8 weeks. So it makes sense to keep using it consistently for at least a month before assessing whether you are noticing a difference.
What happens if you take too much ashwagandha?
No universal safe maximum dose has been established. Taking more than the studied dose brings no predictable additional benefit and may increase the risk of gastrointestinal discomfort or drowsiness. If you feel unusual symptoms, stop and speak with a healthcare professional.
Do ashwagandha gummies have the same dose as capsules?
There are no studies directly comparing gummies with capsules. Gummies usually have less extract per unit, so you may need to take two or more to reach the dose per serving. What matters is checking on the label how many gummies make up the daily serving.
Who should not take ashwagandha?
It is not recommended for children, pregnant or breastfeeding women, or people with thyroid disease or autoimmune diseases. In case of liver disease, other diseases or taking medicines, you should consult a healthcare professional before use.
Sources and references
Informative summary of published research. The results refer to the forms and people studied; they are not promises about the effect of any product.
- Akhgarjand C, Asoudeh F, Bagheri A, et al. Does Ashwagandha supplementation have a beneficial effect on the management of anxiety and stress? A systematic review and meta-analysis of randomized controlled trials. Phytother Res. 2022;36(11):4115-4124. pubmed.ncbi.nlm.nih.gov · PMID 36017529 · DOI 10.1002/ptr.7598
- Alsanie SA, Alhodieb FS, Askarpour M. Effects of ashwagandha (Withania somnifera) on mental health in adults: A systematic review and dose-response meta-analysis of randomized controlled trials. Complement Ther Med. 2026;97:103325. pubmed.ncbi.nlm.nih.gov · PMID 41644067 · DOI 10.1016/j.ctim.2026.103325
- Lopresti AL, Smith SJ, Malvi H, et al. An investigation into the stress-relieving and pharmacological actions of an ashwagandha (Withania somnifera) extract: A randomized, double-blind, placebo-controlled study. Medicine (Baltimore). 2019;98(37):e17186. pubmed.ncbi.nlm.nih.gov · PMID 31517876 · DOI 10.1097/MD.0000000000017186
- Prajapati H, Satia M, Shah D, et al. Efficacy and Safety of Low-Dose Ashwagandha Supplementation on Exercise Endurance: A Randomized, Placebo-Controlled, Double-Blind, Clinical Trial. Phytother Res. 2026;40(8):4978-4987. pubmed.ncbi.nlm.nih.gov · PMID 41846233 · DOI 10.1002/ptr.70178
- Regulamento (UE) n.º 432/2012 da Comissão, que estabelece uma lista de alegações de saúde permitidas relativas a alimentos (versão consolidada no EUR-Lex). eur-lex.europa.eu
- Della Porta M, Maier JA, Cazzola R. Effects of Withania somnifera on Cortisol Levels in Stressed Human Subjects: A Systematic Review. Nutrients. 2023;15(24). pubmed.ncbi.nlm.nih.gov · PMID 38140274 · DOI 10.3390/nu15245015
- Cheah KL, Norhayati MN, Husniati Yaacob L, et al. Effect of Ashwagandha (Withania somnifera) extract on sleep: A systematic review and meta-analysis. PLoS One. 2021;16(9):e0257843. pubmed.ncbi.nlm.nih.gov · PMID 34559859 · DOI 10.1371/journal.pone.0257843
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